DNA OncoScreen by Mapmygenome
Cancer is one of the leading causes of death globally, with nearly 10 million deaths in 2020 alone. Each year, approximately 400,000 children are diagnosed with cancer, further highlighting the disease’s widespread impact. Despite the staggering statistics, cancer is often curable when detected in its early stages. The problem, however, is that less than 20% of cancer patients in India are diagnosed and treated in the early stages due to a lack of awareness and limited access to screening strategies.
DNA OncoScreen is designed to address this gap by offering a comprehensive cancer screening test that assesses genetic risks and biochemical markers. The test analyzes over 700,000 genetic markers across the genome, combined with various biochemical tests, to provide an accurate risk assessment for different types of cancers and known risk factors.
This integrated approach enables individuals to proactively manage their health by identifying cancer risks early and making informed decisions about prevention, treatment, and lifestyle changes.
Why DNA OncoScreen?
Early detection is key to successful cancer treatment. Many cancers, when detected at an early stage, can be treated more effectively, reducing the risk of severe outcomes. However, in countries like India, the lack of widespread cancer screening leads to late-stage diagnoses, making treatment more challenging and reducing survival rates.
DNA OncoScreen provides a solution by identifying potential cancer risks long before symptoms appear. This test empowers individuals with vital information about their genetic predisposition to various cancers, allowing for early intervention, personalized medical advice, and preventive care.
Additionally, the test’s biochemical markers offer insights into various health traits and conditions, helping to detect underlying issues like obesity or hormone imbalances that may contribute to cancer risks.
Conditions Covered by DNA OncoScreen
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Cancers |
Traits |
BIOCHEMICAL TESTS |
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Colorectal Cancer |
Obesity |
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Prostate Cancer (♂) |
Prostate Specific Antigen(♂) |
CBC - Hb, RBC, Total WBC, MCH, MCV, PCV, MCHC, Differential count |
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Lung Cancer |
Nicotine Dependence |
ESR |
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Breast Cancer (♀) |
Alcohol Flush Reaction |
Beta-HCG |
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Bladder Cancer |
Antioxidants |
CUE |
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Melanoma |
Alcoholism |
AFP |
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Hodgkins Lymphoma |
CEA |
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Non Hodgkins Lymphoma |
Fecal occult blood testing |
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Chronic Lymphocytic Leukemia |
CA-125 (♀) |
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Renal Cell Carcinoma |
CA - 19.9 |
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Ovarian Cancer(♀) |
PSA (♂) |
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Thyroid Cancer |
CA-15.3 (♀) |
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Pancreatic Cancer |
LDH (♂) |
Clinical Utility of DNA OncoScreen
The clinical utility of DNA OncoScreen lies in its comprehensive approach to cancer prevention and early detection. By combining both genetic and biochemical testing, the test provides a robust risk assessment for a wide range of cancers. This test is suitable for both individuals with a family history of cancer and those looking to proactively manage their health.
Here are the key benefits of DNA OncoScreen:
- Early Detection: Identifies genetic markers and biochemical signs of cancer risk, enabling early intervention and improved treatment outcomes.
- Personalized Screening: Tailored screening based on individual risk factors and genetic predisposition.
- Comprehensive Testing: Screens for over 700,000 genetic markers across 100+ genes, offering insights into a wide variety of cancers.
- Integrated Risk Management: Combines genetic and biochemical testing to provide a holistic view of cancer risk.
- Prevention and Proactive Care: Helps individuals make informed decisions about lifestyle, medical care, and preventive measures.
- Genetic Counseling: Professional counseling to help individuals understand their risk and create a personalized action plan for cancer prevention and early treatment.
When to Consider DNA OncoScreen
- Family History of Cancer: If you have a family history of cancer, especially if multiple relatives have been diagnosed, DNA OncoScreen can help assess your inherited cancer risk.
- Proactive Health Management: If you are concerned about your risk of developing cancer and wish to take proactive steps, this test is ideal.
- Symptoms or Health Concerns: If you have health conditions that increase your cancer risk, such as obesity, nicotine dependence, or alcoholism, this screening can provide insights into your risk profile.
- Individuals Over 40: Those over 40 years old, especially men for prostate cancer and women for breast and ovarian cancer, should consider regular cancer screening.
- Pre-Symptomatic Screening: Even if you don’t show any symptoms, cancer screening is a valuable tool for detecting cancers early, often before they are noticeable.
MapmyGenome Offerings
MapmyGenome provides a wide range of services in conjunction with the DNA OncoScreen test:
- Powerful Genetic Testing: High-density screening using the globally recognized Illumina platform, analyzing over 700,000 genetic markers.
- Comprehensive Biochemical Testing: Assessment of tumor markers and other biochemical tests for early cancer detection.
- Genetic Counseling: Personalized pre- and post-test counseling to help individuals and families understand their results and make informed decisions.
- Actionable Insights: Detailed reports that provide a roadmap for managing cancer risk, including lifestyle changes, preventive care, and medical recommendations.
Test specifications
|
Technique |
Platform |
Coverage |
Variant types |
TAT |
Sample Requirements |
|
NGS |
Illumina iScan |
700 - 800X |
SNV |
3 - 4 weeks |
1µg - 2µg of DNA Sample, EDTA Blood (2-3ml), 4-5ml in Sodium Citrate tube, 4-5ml in ACD tube, Urine Sample, Stool sample |