Sickle Cell Anemia

About 300,000 babies are born every year with sickle cell anemia. Experts predict this number will pass 400,000 by 20501

Sickle cell anemia is an inherited red blood cells disorder in which the hemoglobin which carries the oxygen throughout the body gets affected. Healthy red blood cells are round, but in people with sickle cell anemia the red blood cells become sticky and hard and look like a C-shaped farm tool called a “sickle”. The sickle cells die early, which causes a continuous shortage of red blood cells. Also, when they travel through small blood vessels, they get stuck and choke the blood flow. This can lead to pain and other significant problems such as infection, stroke and acute chest syndrome.

When should you get tested?

Test specification

Technique Variant types TAT Sample requirements
Sanger sequencing Mutation 3 - 4 weeks 2 ml EDTA Blood / 2 ug DNA